Immuno Concepts was founded in 1979 with a commitment to advance the quality of diagnostic assays for systemic rheumatic diseases.
In 1979 Immuno Concepts pioneered the conversion from rodent tissue to HEp-2 cells for detection of anti-nuclear antibodies (ANAs). Using genetic engineering they developed HEp-2000®, an ANA substrate with increased sensitivity for detection of autoantibodies to SS-A/Ro. The advantages of the HEp-2000® substrate over conventional HEp-2 have been documented in over thirty published papers from well-known institutions.
Immuno Concepts was the first company to offer a non-fluorescent ANA. The Colorzyme® methodology uses a patented stabilized color reagent system that allows slide-based assays to be read using common bright field microscopy. The Colorzyme® format is available for our ANA and nDNA slide assays.
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